APV Webinar - Macaque Model of Severe ARDS Resulting form Inhalation of Highly Pathogenic Avian Influenza Viruses

Wednesday, November 29th from 1:00 PM - 2:00 PM Central Time

$115 for Members

$175 for Non-members

Registration is now OPEN! Please click HERE for registration.

Within 1 to 3 business days after ordering the webinar, you will be sent an email with a link to register and view the webinar on the GoToWebinar website.


This live webinar will describe the development of a macaque model of highly pathogenic avian influenza, describe how aerobiology, radiotelemetry, and plethysmography were instrumental in creating this model, and how this model can be used to evaluate potential vaccines. refinements made to the model that have improved its utility in assessing potential vaccines and treatments will be discussed. A live questions and answer session will occur at the end of the webinar.

PRESENTER: Douglas Reed, PhD

"I am a tenured Associate Professor of Immunology with more than two decades of experience in studying acute respiratory infections that cause severe morbidity and mortality, particularly in large animal models. I am an internationally recognized expert in the exposure of animals to aerosols containing viruses and bacteria, to develop models that can be used to explore the pathogenesis of disease, the host response to infection, and to evaluate efficacy of potential vaccines and therapeutics. This has included investigating the physiological response to infectious insult including changes in body temperature, respiratory function, electrocardiography, and electroencephalography measured by radiotelemetry devices implanted in the animal or plethysmography. I have developed animal models for tularemia, filoviruses, alphaviruses, and Rift Valley Fever virus. My lab in conjunction with Dr. Simon Barratt-Boyes here at the University of Pittsburgh developed the first macaque model of lethal acute respiratory distress syndrome resulting from inhalation exposure to highly pathogenic avian influenza. I am a PI on an NIH-funded contract and a grant from the Bill & Melinda Gates Foundation to evaluate influenza vaccines for efficacy against in the macaque model, as well as an NIH contract for initial screening of monoclonal antibodies and vaccines against influenza viruses including highly pathogenic avian influenza. I am PI or Co-PI on grants and contracts for other pathogens as well that are funded by NIH or DOD. I have served on the University of Pittsburgh’s IACUC and IBC for 12 years combined and continue to serve as a reviewer for NIH and DOD grant applications and for a variety of scientific journals."

  • Brief review of the ongoing H5N1 pandemic and the risk of ongoing spillover events that could lead to the next human pandemic.
  • Importance of the macaque animal model to study H5N1 disease pathogenesis, vaccines, and treatments.
  • Overview of aerobiology and radiotelemetry and their utility in the study of infectious disease.

This program has been RACE approved for 1 hour of continuing education credit in jurisdictions which recognize RACE approval.